NR5A1 and disorder of sexual differentiation: Notably, WES detected some variants of previously known DSD-causing genes, including the c.132_134del (p.Asn44del) heterozygous in-frame-deletion in NR5A1 (Figure 2A) and heterozygous nonsynonymous variants of unknown significance (VUS) in DHX37 and SLC26A8, which may be involved in DSD development.