As shown in Figure 2, age-specific tdAUCs of PSA with 10-year incidence risk of PCa in participants aged <60, 60–64, 65–69, and ≥70 years groups were 0.832, 0.808, 0.806, and 0.809, respectively, and age-specific PSA cut-off values were 1.41, 1.46, 1.59, and 2.12 ng/mL, respectively. Here, KLK3 is linked to posterior cortical atrophy.