KLK3 and posterior cortical atrophy: As shown in Table 1, the risk of both PCa incidence and mortality in participants with positive PSA were higher than those with negative PSA in low-PRS group [(18.33 vs. 2.59 per 1,000 PYs); (0.75 vs. 0.25 per 1,000 PYs)], similar trend was observed for high-PRS group [(41.89 vs. 5.35 per 1,000 PYs); (1.53 vs. 0.40 per 1,000 PYs)].