TET2 and chronic myelomonocytic leukemia: The Tet2 KO mice had expanded hematopoietic stem cell and progenitor cell populations (Li et al., 2011; Moran-Crusio et al., 2011; Ito et al., 2019), which induced disorders in myeloid and lymphoid cell lineages mimicking chronic myelomonocytic leukemia (CMML) (Moran-Crusio et al., 2011; Ito et al., 2019).