Furthermore, studies have linked NFE2L3 to other cancers such as lung adenocarcinoma (Ren J. et al., 2020), malignant pleural mesothelioma (Wang et al., 2022), and ovarian cancer (Dou et al., 2022), indicating its potential as a target for innovative cancer treatment approaches. Here, NFE2L3 is linked to lung adenocarcinoma.