CDIN1 and hydrops fetalis: We confirmed that for the antibody previously used in HEK293 cells40, immunofluorescence signal did not decrease upon siRNA-mediated knockdown of CDIN1 (Supplemental Fig. 1c,d) or HP3-mediated degradation of CDIN1-HF (Supplemental Fig. 1e,f), suggesting that the antibody is nonspecific37.