The DE genes were significantly over-represented (Bonferroni-adjusted p-value <0.05) for KRAS upregulation and drug metabolism pathways (Figure S5B) while DS genes were significantly over-represented (Figure S5C) in G2M checkpoint, mitotic spindle, and nucleotide excision repair pathways, suggesting a potential for these events to impact cellular functions, contribute to the cancer disease state, and/or play a role in regulatory mechanisms of gene expression. This evidence concerns the gene KRAS and cancer.