After adjusting for traditional risk factors, significant inverse associations between succinate and plasma insulin levels (β = −0.02, p = 4.5E-04), homeostatic model assessment of insulin resistance (HOMA-IR; β = −0.023, p = 4.2E-04), BMI (β = −0.004, p = 0.002), and waist-to-hip ratio (β = −0.001, p = 6.0E-04) were observed, and a positive association was observed with HDL-C (β = 0.010, p = 4.4E-04). This evidence concerns the gene INS and Insulin resistance.