According to Divanoglou N et al., elderly residents of a homogenous rural population in central Greece exhibited a high prevalence of vitamin D deficiency, which was associated with VDR gene polymorphisms, specifically the cumulative effect of three different genotypes: BsmI, TaqI, and FokI. These findings underscore the significant correlation between VDR gene polymorphisms and serum vitamin D levels, highlighting the persistence of vitamin D deficiency in regions with abundant sunlight, such as Greece. This evidence concerns the gene VDR and vitamin D deficiency.