However, in our study, the use of quercetin did not benefit the case AU, who had slow genotypes in CYP1A1 rs1048943-TT [42], COMT rs4680 -AA [53], rs4633-TT [54] and MAO rs6323-TT [47] (Table 1), and urinary incontinence was observed after quercetin use (Table 6). This evidence concerns the gene COMT and Urinary incontinence.