In tumor samples, ApcMin/+Ret+/− males had significantly higher Apc expression than both ApcMin/+Ret+/− females (2,160 ± 80 AU vs 1,854 ± 55 AU, p<0.02, Student’s two-tailed t-test) and ApcMin/+ males (2,160 ± 80 AU vs 1,885 ± 29 AU, p=0.02, Student’s two-tailed t-test). The gene discussed is APC; the disease is neoplasm.