Immunization of mice with another multi-chaperone vaccine purified from the mouse sarcoma cell line S180 containing the mixture of HSP60, HSP70, HSP110 and gp96 (mHSP/peptide vaccine) in combination with cyclophosphamide and IL-12 suppressed tumor growth and improved long-term survival (169). The gene discussed is HSP90B1; the disease is neoplasm.