- Lung, blood and spleen: CD11b+/Ly6G+ Neu expansion <-> no accumulation in TME- BM: twofold expansion of LSK fraction with an increased HSCs (8wks), MPP (at 10wks) and GMPs while no significant change in CMPs + decreased erythropoiesis resulting in anemia<-> unlike BM, majority of spleen-residing myeloid precursors were MEPs. The gene discussed is ITGAM; the disease is anemia (phenotype).