ZDHHC6 and colorectal carcinoma: In addition, the expression of ZDHHC6 by ectopic expression in HCT116, SNU-C2A, SW48, HT-29, and Caco-2 cells led to an increase in the expression of PPARγ protein and a speeding up of its translocation to the nucleus of the CRC cells (Fig. 7D, E).