ZDHHC6 and colorectal carcinoma: Given the strong association between ZDHHC6 and PPARγ, as well as the crucial role of ZDHHC6 as a palmitoyltransferase in various biological processes, we hypothesized that ZDHHC6 may regulate the palmitoylation of PPARγ in response to alterations in lipid metabolism that occur during the progression of CRC.