Conversely, significant positive correlations were noted between the frequency of Neu, Th1/Th2 index in the liver and α-SMA folds or collagen area, the frequency of M1 or M2 with the collagen area, the M1/M2 or Th1/Th2 index in the liver with early or average granuloma areas, and the Th1/Th2 index with the area of mature granuloma. Here, ACTA1 is linked to Granuloma.