We confirmed the association of endogenous UBL3 with the RNA-binding proteins FUS and HPRT1—both listed in the Neurodegenerative Diseases Variation Database (NDDVD)—and with LYPLA1, which is involved in Huntington’s disease, using immunoprecipitation (IP)-western blotting analysis. This evidence concerns the gene LYPLA1 and juvenile Huntington disease.