The first study involving 18 apolipoprotein A-I (AApoA-I) amyloidosis patients with liver involvement found an average liver stiffness of 21.9 (± 18.3) kPa compared to 6.05 (± 4.6) kPa in the 76 AApoA-I amyloidosis patients without liver involvement [33]. This evidence concerns the gene APOA1 and amyloidosis.