We found that manipulation of Serpinb2+ neuronal activity did not affect locomotion in an open field test (Extended Data Fig. 5a,b), conditioned place preference (CPP) (Extended Data Fig. 5c), cocaine CPP test (Extended Data Fig. 5d), anhedonia in sucrose preference test (Extended Data Fig. 5e), social interaction (Extended Data Fig. 5f,g) or anxiety in the elevated plus maze test (Extended Data Fig. 5h,i). Here, SERPINB2 is linked to Anxiety.