Notably, many of the human orthologues have been associated with nervous system diseases (ADAMTSL4, CCDC171, CD2D3, COL4A2, COL6A2, CSF1R, CLU, DPP6, FCN1, HBA1, HBB1, ITIH2, IRS2, JPH, MRVI1 PRDX2, SLC25A20, SYN2, ZNF367) (S1 Table). Here, SYN2 is linked to nervous system disorder.