CD8A and infection: This analogy between inhibition of apoptosis and inhibition of necroptosis also extends to the CD8 T-cell response that was enhanced compared to the WT virus control for all viral epitopes tested after infection with mCMV-M45fs lacking functional M45, and was reversed to WT levels for mCMV-M45fs-Rev expressing functional M45 (compare Fig 2B with Fig 6C).