Downregulated KEGG pathways (padj < 0.05) in response to exogenous GLP-2 administration include ribosome, RNA transport, DNA replication, ribosome biogenesis in eukaryotes, spliceosome, cell cycle, base excision repair, mismatch repair, nucleotide excision repair, primary immunodeficiency, RNA polymerase, Fanconi anemia pathway, B cell receptor signaling pathway, and leishmaniasis (Table 4). This evidence concerns the gene GCG and leishmaniasis.