The finding that T cells identified by these IsoLG-modified peptides are present in the aorta and kidney of hypertensive mice is compatible with prior work in which we showed that an oligoclonal population of CD8+ T cells accumulate in the kidneys of hypertensive mice and that T cells with a memory phenotype home to the bone marrow in hypertension (46). The gene discussed is CD8A; the disease is Hypertension.