To evaluate the role of PEAR1 in TNBC cells, we generated stable PEAR1-knockdown (shPEAR1) and PEAR1-overexpression (oe-PEAR1) MDA-MB-231 and SUM159 cell lines using lentivirus infection, which we confirmed with quantitative real-time PCR (RT-qPCR) and Western blotting (Supplemental Figure 2, A and B). The gene discussed is PEAR1; the disease is lentivirus infection.