FH and acquired polycythemia vera: Since our cohorts only included one patient with germline FH PV, an analysis of metabolic parameters for the identification of such individuals is not possible; however, asparagine, asparagine/2-hydroxyglutarate, fumarate/2-hydroxyglutarate, malate/2-hydroxyglutarate, and glutamine/2-hydroxyglutarate are possible markers that should be investigated in a larger cohort (Table 3).