Among the four SNP loci in the paternal HLA-G gene, the frequencies of the rs1630185G (OR = 1.644, 95% CI = 1.005∼2.688, p = 0.046) and rs1130363A (OR = 1.644, 95% CI = 1.005∼2.688, p = 0.046) alleles were lower in the preeclampsia group than in the control group. The gene discussed is HLA-G; the disease is preeclampsia.