Among the four SNP loci in the fetal HLA-G gene, the frequencies of rs9380142A (OR = 2.802, 95% CI = 1.761∼4.458, p = 0.001) and rs1063320G (OR = 1.807, 95% CI = 1.144∼2.852, p = 0.01) were greater in the preeclampsia group than in the control group. Here, HLA-G is linked to preeclampsia.