Moreover, after adjusting for age, gender, education, DM duration, and the prevalence of hypertension, the association between higher levels of Galectin-3 and increased risk of MCI remained significant, with an adjusted OR of 2.028 (95% CI: 1.570–2.620, p < 0.001; Table 4). The gene discussed is LGALS3; the disease is Hypertension.