SLC5A2 and glomerulosclerosis: 1. Block the reabsorption of sodium and glucose by SGLT2, and condense the afferent arterioles2. Increase podocyte autophagy, reduce podocyte lipid content, and protect podocyte3. Inhibition of YAP/TAZ activation and CYP4A/20-HETE signaling to alleviate tubulointerstitial fibrosis or glomerulosclerosis