The beneficialeffects of MEAI were further corroborated by improved HOMA-IR andISI scores (Figure 7G,H), which are recognized markers of insulin resistance/sensitivity.These findings collectively suggest that MEAI exerts a positive influenceon glucose homeostasis, potentially by improving the body’scapacity to utilize insulin and maintain healthy blood sugar levels.Interestingly, the circulating levels of adiponectin, an adipokine-relatedhormone known for its insulin-sensitizing properties, remained unchangedacross all groups (Figure 7I). The gene discussed is ADIPOQ; the disease is Insulin resistance.