The results of radioliganddisplacement assays indicated that MEAI exhibited modest binding inhibitionto the 5-HT2B receptor, while the other targets were unaffected.35 Furthermore, the findings suggest that MEAI’slack of inhibitory activity on MAO-A, MAO-B, and VMAT may mitigatethe risk of cardiovascular crisis and serotonin syndrome, which areassociated with 5-HT2B activation. This evidence concerns the gene MAOB and serotonin syndrome.