CDK4 and neoplasm: Meanwhile, we found that NLRP3 overexpression also promoted the tumor cell viability (Figure 7(a)–7(c)), invasion (Figures 7(d) and 7(e)), and migration (Figures 7(f) and 7(g)), as well as the expression of cyclin D1, CDK4, MMP-2, MMP-9, and vimentin but downregulated E-cadherin expression (Figures 7(h) and 7(i)) after LPS treatment.