The results showed that samples from the high-risk group were significantly enriched for cancer-related signaling pathways such as cell cycle, DNA replication, mismatch repair, and P53 signaling pathway; and the low-risk group was enriched for a variety of metabolism-related pathways such as butyrate metabolism, primary bile acid biosynthesis, and metabolic pathways such as leucine and isoleucine degradation. The gene discussed is TP53; the disease is cancer.