Interestingly, PTTG1, DLGAP5, and ANLN were also included in the metabolically relevant prognostic and immunotherapeutic profiles of lung adenocarcinoma in a recent study (71), suggesting that the relevant prognostic profiles that we constructed do indeed reflect the metabolic profiles of lung adenocarcinoma at the transcriptional level to some extent. This evidence concerns the gene PTTG1 and lung adenocarcinoma.