NET-DNA can bind to coiled-coil domain containing protein 25 (CCDC25) on cancer cells, activating the integrin-linked kinase (ILK)-β-parvin-ras-related C3 botulinum toxin substrate 1 (RAC1)-cell division control protein 42 (CDC42) cascade within cancer cells[63] [Figure 5B]. The gene discussed is CCDC25; the disease is cancer.