XIST and Autoimmunity: Since most of our results pertaining to loss or gain of marker genes are similar in males and females, the study does not yet address reasons for sex‐biased immune aging: it would for example be interesting to evaluate whether XIST‐protein complexes recently implicated in enhanced female autoimmunity (Dou et al., 2024) change in abundance with age, though we did not observe an age difference in XIST transcript levels.