Among proteins uniquely associated with specific infections, we observed lower levels of MME (aka neprilysin; primary Aβ degradation enzyme) with influenza, higher levels of TREM2 (myeloid receptor) with HHVs, higher levels of IFIT3 (interferon-induced antimicrobial peptide) with URTIs, and higher levels of ADAM17 (TREM2-sheddase) with skin and subcutaneous infections. This evidence concerns the gene TREM2 and infection.