In two cases, the identification of entity-specific fusions suggested a re-classification of a meningioma CNS-WHO grade 2 to intracranial mesenchymal tumor (ATF1::ESWR1 fusion) and glioblastoma to a polymorphous low-grade neuroepithelial tumor of the young (PLNTY, FGFR2::CTNNA3 fusion). This evidence concerns the gene FGFR2 and glioblastoma.