AFP and neoplasm: In a multivariable univariate Cox regression, a major pathologic response was not predictive of RFS (HR 0.62, 95% CI, 0.03–11.03) when controlled for variables, including albumin–bilirubin (ALBI) grade, AFP ≥ 400 ng/mL, tumor size ≥ 5 cm, tumor focality, R0 resection status, vascular invasion on final pathology, and tumor grade.