Specifically, disruption of sleep homeostasis can lead to the oscillatory changes as seen here, and sleep disruption is a cardinal feature of Morvan syndrome associated with CASPR2 autoantibodies(Binks et al., 2018; Irani et al., 2012; Vincent et al., 2018); detailed analysis of the rodent sleep video-EEG is the goal of future studies. The gene discussed is CNTNAP2; the disease is Morvan syndrome.