To investigate the effects of Setd1a haplosufficiency on ASR and PPI further, and also to further explore the possible links between Setd1a and schizophrenia, we used the antipsychotic drugs risperidone or haloperidol with a second naïve cohort of mice (Cohort 2), divided into two groups; one for each drug. The gene discussed is SETD1A; the disease is schizophrenia.