Given that lncRNA negatively correlated with miRNA in cancer, STK4‐AS1, and AC068338.2 were screened as candidate upstream ncRNAs which negatively regulate miR‐106b‐5p expression in KIRC, suggesting that STK4‐AS1 and AC068338.2 as an independent risk factor and preclinical marker in KIRC and may be associated with KIRC pathogenesis (Tables S4 and, S5). This evidence concerns the gene STK4 and cancer.