LMNA and laminopathy: Given that laminopathy-associated lamin mutants show distinct differences in their phosphorylation states (Torvaldson et al., 2015;, Cenni, 2005;, Mitsuhashi et al., 2010;, Swift et al., 2013), we first assumed that the mutated lamin A was constitutively active (dephosphorylated).