In another study in rats, lower IL‐6, TNF‐α, and IL‐1β expression and higher IL‐10 were observed in the group given kefir in addition to experimental periodontitis, compared to experimental periodontitis (Vieira, de Sousa, et al., 2021; Vieira, Rosario, et al., 2021). This evidence concerns the gene IL10 and periodontitis.