Through univariate Cox and log-rank test analyses, we discerned that FCN1 exhibited prognostic significance across a spectrum of cancers, excluding BRCA, KICH, KIRP, Pheochromocytoma and Paraganglioma (PCPG), Rectum adenocarcinoma (READ), Thyroid carcinoma (THCA), and UCEC (Supplementary Figure S10A). This evidence concerns the gene FCN1 and rectum adenocarcinoma.