NFKB1 and cystic fibrosis: Abnormal proliferation and differentiation of cardiac fibroblasts (CFB) can promote CF, and SalB inhibits Ang II-induced CFB activation and proliferation, as well as the fibrotic process by suppressing the expression of NF-κB and pro-fibrotic factors and ECM accumulation (Fan and Guan, 2016; Wang et al., 2018).