Liu et al. employed molecular docking and ion resonance biosensors to illustrate the strong binding affinity between PDGFR-β and SalB, and SalB relieves HF by inhibiting the PDGFR-β signaling pathway and inducing HSC apoptosis, and inflammatory reaction of HSC (Liu et al., 2023b). The gene discussed is PDGFRB; the disease is hydrops fetalis.