ATXN7 and spinocerebellar ataxia 7: In SCA7, CAG trinucleotide expansion in the ataxin-7 gene (ATXN7) results in the accumulation of a poliQ stretch at the N-terminal of the protein and longer CAG trinucleotide expansions are correlated with early onset and greater overall severity of the disease (Goswami et al., 2022).