Similarly, exosomes miR-625-3p and LINC00659 also promote CRC cell migration, invasion, and EMT by inhibiting the Elav-like family member 2/WW domain-containing oxidoreductase (CELF2/WWOX) pathway and interacting directly with miR-342-3p, respectively (Zhang et al., 2022b; Zhou et al., 2021). The gene discussed is WWOX; the disease is colorectal carcinoma.