IL6 and diabetes mellitus: The restricted cubic spline curve showed that afteradjustment for gender, diabetes, clopidogrel, ticagrelor,triglyceride, APOA/B, and HbA1, the risk of progression of NTL of coronary arterygradually increased with the increase of IL-6 level, and there exited anon-linear relation between IL-6 and progression of NTLs (p< 0.001)(Fig. 1).