Studies havereported that the protein expressions of NLRP3 and caspase-1 in circulatingmonocytes among patients with acute coronary syndrome were increased [22].Similarly, the NLRP1 inflammasome were found to increase in patients with primaryatherosclerotic lesions and inflammasome complex was activated by interactionwith NLRP1 and NLRC4 receptors [24]. This evidence concerns the gene CASP1 and acute coronary syndrome.