Our data show that infiltrated monocytes/macrophages abundantly express A3R. Induction of Adora3 and A3R has been previously demonstrated in peripheral lymphoid (Wei et al., 2013) and inflamed spinal cord tissue during EAE (Wei et al., 2013; Jakovljevic et al., 2017), as well as during ischemia, hypoxia, and subarachnoid hemorrhage (Coppi et al., 2023). This evidence concerns the gene ADORA3 and subarachnoid hemorrhage.