lncRNAs are highly expressed in a variety of malignant tumours and are closely associated with patient prognosis, such as ALAT1, ANRIL, H19, CUDR, Zeb3 and other lncRNAs have been found to be highly expressed in lung cancer, breast cancer, colon cancer and other malignant tumors, playing the role of oncogenes, and are considered to be novel biomarkers for predicting the prognosis of human cancers [18]. The gene discussed is H19; the disease is breast cancer.