the results of the meta-analysis showed that it was combined in studies of the degree of differentiation with colorectal cancer (OR=0.45, P<0.01), in studies of the relationship with the presence or absence of lymph node metastasis (OR=0.59, P<0.01), and in studies of total survival studies (HR=1.34, P<0.001), patients in the high NEAT1 expression group had shorter OS with a combined effect size of [HR=1.34, 95%CI=1.21–1.48]. Here, NEAT1 is linked to metastatic malignant neoplasm in the lymph nodes.