Even though it is regarded that increased abdominal obesity promotes pro-inflammatory milieu in AP patients, RBP4 was not correlated with waist circumference (WC) in two studies conducted by Singh et al. [64], [65], although significant and independent correlation between RBP4 and WC was confirmed in overweight/obese otherwise healthy population [66]. Here, RBP4 is linked to alkaline phosphatase measurement.