Hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN) is a rare, progressive, irreversible, and life-threatening autosomal dominant disorder predominantly caused by single-point mutations in the transthyretin (TTR) gene encoding TTR, a thyroxine and vitamin A transporter [1–4]. Here, TTR is linked to poikiloderma with neutropenia.