Interestingly, ZNF582 methylation displayed 85% sensitivity and 87% specificity for discriminating mild dysplasia or worse oral lesions, whereas PAX1 methylation showed 72% sensitivity and 86% specificity for discriminating moderate dysplasia or worse oral lesions, emphasizing the potential of both markers for the detection of oral dysplasia and OC [15]. The gene discussed is ZNF582; the disease is dysplasia.